Bob DeMarco centered the Cardinals throughout the 1960s, debuting in 1961 and becoming a starter the year after. DeMarco was solid throughout the decade, netting three Pro Bowls (1963, 1965 & 1967), with the last of the three also seeing him with a First Team All-Pro.
DeMarco left St. Louis after the 1969 season, playing five more years in the NFL. DeMarco started all but five of his 107 Games with the Cardinals, and the franchise never had to worry about Center for eight strong years.