Starting his Major League career with the Milwaukee Brewers in 2008, Escobar became a starting infielder in 2010. He had his best years after he was traded to Kansas City in 2011. While Escobar did not have a power game, hitting only 58 home runs in 1,552 games, he was known for his exceptional fielding and base running abilities. He recorded at least 20 stolen bases seven times, with a total of 253 SB. Escobar also had three seasons where he broke 1.5 in Defensive bWAR. His best year was in 2015 when he was an All-Star, won the Gold Glove, and played a pivotal role in the Royal World Series win that year. Escobar won the ALCS MVP, batting .478 with 5 RBIs, and he hit an inside-the-park home run in the World Series.
Over the course of his career, he had 1,486 hits.